What is treatment success in cardiac resynchronization therapy?

Great Expectations: MicroRNA-30d and Cardiac Resynchronization Therapy Running title: Dorn; miR-30d as a biomarker for resynchronization success

Role of inotropic agents in the treatment of heart failure.

Systolic heart failure (HF) is a systemic disease caused by reduced cardiac contractility. Although it would seem logical that this disease could be treated with strategies to directly improve contractility, inotropic therapies in the HF population have universally failed to live up to their expectations. Paradoxically, favorable outcomes can be achieved by administering drugs that may transien...

Ventricular Resynchronization: an Emergent Therapy

Rev Esp Cardiol 2004;57(4):279-82 279 Cardiac resynchronization therapy (CRT) is a new invasive technique. The devices used are expensive, the implantation procedure is usually lengthy, sometimes complex, and the technique is not exempt from complications. Despite these limitations, however, CRT has experienced great progress over recent years, both clinically and experimentally. To what, then,...

Treatment of the heart failure patient with atrial fibrillation: a major unmet need.

Treatment of chronic heart failure (HF) in patients with reduced left ventricular (LV) ejection fractions (HFREF) has markedly improved in the last 20 years. Beginning with the success of neurohormonal inhibition in the 1990s and 2000s, the introduction of cardiac resynchronization therapy in the mid-2000s and, most recently, demonstration that heart rate (HR) slowing with ivabradine therapy (1...

Cardiac resynchronization therapy for congestive heart failure.

Cardiac resynchronization represents a novel therapeutic strategy for the treatment of congestive heart failure due to systolic dysfunction. Since its modest beginnings in the 1990s, cardiac resynchronization therapy has gained widespread acceptance as a useful adjunct to pharmacologic therapy for congestive heart failure. Randomized trials have consistently shown functional improvement in pati...